Laboratory for Genome Expression Regulation

Scientific results:

1. We have researched the molecular mechanisms of the control of the activity of enhancers, the functioning of insulators, the formation of the top chromatin structures. 
2. Our researchers have studied the structure of the architectural factors of chromatin, transcription factors and RNA-binding proteins controlling the  expression of genes. 
3. We have proposed new models of various stages of the process of gene expression. 
4. We have determined the molecular foundations of a number of ontogenesis processes, the formation of cell polarity, the functioning  of the nervous system.

Education and career development:

• One Doctor of Sciences dissertation, 7 Candidate of Sciences dissertations, 10 master’s, bachelor’s and specialist’s degree theses have been prepared and defended.
  
• One scientific school has been conducted. 

Organizational and structural changes:

Employees of the Laboratory participate in the work of the Center for Genomics Research of the Institute of Gene Biology of the Russian Academy of Sciences. 

Collaborations:

• Princeton University, Scripps Research Institute (USA), 

• University of Naples Federico II, IRET – Institute of Research on Terrestrial Ecosystems, CNR (Italy), 

• FAME Laboratory, Center for Research and Technology Thessaly (Greece), 

• Laboratory of Immunopathology, Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk (Poland), 

• Research Center of Genetics and Life Sciences of the «Sirius» University of Science and Technology, 

• Laboratory of Intercellular Signaling in the Norm and in Pathology of the V. A. Engelhardt Institute of Molecular Biology of the Russian Academy of Sciences, 

• Laboratory of Animal Biochemical Genetics of the Institute of Molecular Genetics of the National Research Center «Kurchatov Institute», 

• Laboratory of Neurogenetics of the I. P. Pavlov Institute of  Physiology of the Russian Academy of Sciences, 

• Department of Biology and General Genetics of the Faculty of General Medicine of the I. M. Sechenov First Moscow State Medical University of the Ministry of Health of Russia (Sechenov University), 

• Research and Education Center «Photonics and IR engineering» of the Bauman Moscow State Technical University (Russia): joint research and publications.